Patients with interleukin 28BCC genotype had a slightly better response to hepatitis C treatment with pegylated interferon, ribavirin and telaprevir than those with the CT or TT genotypes in a recent study.Researchers performed genetic testing on 527 patients with hepatitis C genotype 1 to detect polymorphisms of the IL28B gene. All participants had been enrolled in the REALIZE study, in which patients randomly were assigned either placebo (n=105) or 750 mg telaprevir every 8 hours for 12 weeks (n=422), in addition to 180 mcg weekly of pegylated interferon alfa-2a and between 1,000 mg and 1,200 mg ribavirin daily for 48 weeks.
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Active lifestyle appears as beneficial as structured exercise
Inflammatory marker IL-6 indicates disease severity, predicts treatment failure in ulcerative colitis
Monitoring cholesterol, other parameters urged for children with HIV
Vitamin D deficiency linked to ulcerative colitis activity
Patients with hypertension increase physical activity, reduce blood pressure levels after TKA
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