High bone mass linked to greater fat mass in women

The literature suggests that BMI is elevated among patients with high bone mass. In a recent analysis, researchers from the United Kingdom investigated this association and found that high bone mass is related to higher fat mass, reflecting a causal pathway. “We found that in high bone mass, women fat mass is elevated, with a particular tendency toward central adiposity. High bone mass cases are thought to have a genetic predisposition to their raised bone mass density, suggesting a causal pathway whereby raised bone mass density leads to increased fat mass. Several observations support a primary bone phenotype with secondary fat effects,” the researchers wrote.







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