Denosumab reduced wrist fracture in postmenopausal women with osteoporosis

Upon further analysis of data from the FREEDOM trial, researchers confirmed that denosumab significantly improved radius bone mineral density, mass and strength compared with placebo, besides significantly reducing the risk for wrist fracture.Researcher James A. Simon, MD, CCD, NCMP, FACOG, of George Washington University, and colleagues determined the effects of denosumab (Prolia, Xgeva; Amgen) on radius cortical and trabecular bone density, mass, strength and wrist fracture incidence from the study in which postmenopausal women with osteoporosis (n=7,808) received placebo or denosumab 60 mg every 6 months for 36 months.







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